Informasi Detail
| Call Number | : | 711 za d 2012 - 1 |
| Judul | : | Daya Antihelmintik Rebusan Akar Delima (Punica Granatum L) terhadap Cacing Tambang Anjing In Vitro |
| Judul Asli | : | |
| Judul Seri | : | |
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| Pengarang | : | ZAMAN/08711228 HAIRU PEMBIMBING: ISTI'ANAH SITI |
| Subyek | : | 1.DAYA ANTIHELMINTIK 2.AKAR DELIMA 3.CACING TAMBANG ANJING IN VITRO |
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| Abstrak | : | Background : Worms disease was a health issue that occurs abroad and in Indonesia. This was supported by Indonesia's tropical climate, which made possible for the worms, especially the Soil Transmitted Helminths to proliferate rapidly. The high prevalence of intestinal worms in Indonesia resulted in some disadvantages of declining state of health, nutrition, intelligence and productivity of the sufferers as well as anemia. Indonesia has many plants that can be used to treat various diseases. Therefore, it was necessary to find another worm drug derived from plants as an effective alternative drug to eradicate of the hookworms. One of the alternatives that could be used was the root of pomegranate (Punica granatum L). Objectives of the Research : This study had several objectives. First was to find out whether the root decoction of pomegranate (Punica granatum L) had hookworm antihelmintic ability. Second was to determine the LC 50 and LC 90 decoction of the roots of pomegranate (Punica granatum L) an antihelmintic. Last was to determine LT 50 and LT 90 with a decoction of pomegranate root of the concentration variation ( 50%, 25% and 12.5%). Research Method : This study was an experimental study using 5 treatment groups consisting of 3 groups with a concentration of 50%, 25% and 12,5% of the root decoction of pomegranate and also 2 control groups. The positive control group used the pirantel pamoat and the negative control group used 0.9% of NaCl. The research was carried out in two stages those were preliminary studies to determine the length of time when the worms lived outside the host body and the primary research conducted with 4 times of the replication. Each group was analyzed by Probit analysis method, One Way Annova and followed by Bonferroni Post Hoc Test. Result : The preliminary test results on the long lived of hookworm outside the dog?s body was for 15 hours. The main test results indicated the root decoction of pomegranate (Punica garanatum L) with a concentration of 50%, 25% and 12.5% had an antihelmintic ability in vitro and had LD 50 of 8.45% and LD 90 of 19:19%. Lethal time 50 (LT 50) concentration of 50%, 25% and 12,5% is 164.80 minutes, 198.34 minutes and 247.40 minutes. Lethal time 90 (LT 90) concentration of 50%, 25% and 12,5% is 317.13 minutes, 353.68 minutes and 469.21 minutes. Keywords : antihelmintic, root decoction, pomegranate, Punica granatum L, hookworms |
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| Lokasi | : | Perpustakaan Pusat UII |
| Jenis | : | Skripsi |
| DDC | : | 711 |
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| Penerbit | : | Fakultas Kedokteran UII |
| Tahun Terbit | : | 2012 |
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| ISBN / ISSN | : | / |
| Jumlah Eksemplar | : | 1 |
| Jumlah Tersedia | : | 0 |
| Jumlah Ditempat | : | 0 |
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| Informasi Digital | ||
| Abstrak | : | abstract.pdf |
| Cover | : | cover.pdf |
| Daftar isi | : | daftar isi.pdf |
| Preliminary | : | preliminari.pdf |