Informasi Detail
| Call Number | : | 613 Wij a 2014 - 1 |
| Judul | : | Aktivitas Antihiperglikemia Pemberian Bersama Ekstrak Etanol Daun Yacon (Smallanthus Sonchifolius) dan Daun Pahitan (Tithonia diversifolia) pada Tikus Jantan Galur Wistar yang Diinduksi Aloksan |
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| Pengarang | : | WIJAYA/09613209 INDRAJI IDHAM PEMBIMBING: ANSHORY T HADY PRADANA DIMAS ADHI |
| Subyek | : | 1.DAUN YACON 2.DAUN PAHITAN 3.KADAR GULA DARAH |
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| Abstrak | : | Yacon (Smallanthus sonchifolius) and pahitan (Tithonia diversifolia) are plants of the Asteraceae family member that have been proven having antihyperglycemic activity. Some related research about antihyperglycemic activities of these plants did not showed a decrease in blood glucose level to normal limit. Therefore an experimental study by combining administration of the plants extract was undertaken. This study was conducted to determine the antihyperglycemic activity of combine administration of ethanol extract of yacon and pahitan leaves in male Wistar rats induced by alloxan 150 mg/kgBW on 1st day and 75 mg/kgBW on 3rd day with fasting blood glucose parameters. A number of 35 male Wistar rats were divided into 7 groups (N=5). Group I was untreated, group II was only induced by alloxan 150 mg/kgBW ip, group III was induced by alloxan 150 mg/kgBW then treated with glibenclamide 0.45 mg/kgBW, group IV and V were induced by alloxan then treated with ethanol extract of yacon leaves 600mg/kg and ethanol extract of pahitan leaves 1050 mg/kgBW, respectively, VI and VII were induced by alloxan then treated with combined administration ethanol extract extract of yacon leaves and ethanol extract of pahitan leaves 150 mg/kgBW and 787.5 mg/kgBW, and 450 mg/kgBW and 262.5 mg/kgBW, respectively. Measurement of blood glucose fasting levels was performed before alloxan was injected, on the 4th day, and on the 11th day by taking the blood of rats that had previously been fasted. The results showed that the fasting blood glucose levels of male Wistar rats were decreased 33.31%, 57.51%, 50.81%, and 48.86% after receiving treatment 1, treatment 2, treatments 3 and treatments 4, respectively. In conclusion, the dose of combine administration was less effective than a single dose of ethanol extract of pahitan leaves in decreasing blood glucose levels. Keywords : Yacon leaves, pahitan leaves, blood glucose, alloxan, male Wistar rats |
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| Lokasi | : | Perpustakaan Pusat UII |
| Jenis | : | Skripsi |
| DDC | : | 613 |
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| Penerbit | : | Jurusan Farmasi FMIPA UII |
| Tahun Terbit | : | 2014 |
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| ISBN / ISSN | : | / |
| Jumlah Eksemplar | : | 1 |
| Jumlah Tersedia | : | 0 |
| Jumlah Ditempat | : | 0 |
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| Informasi Digital | ||
| Abstrak | : | abstract.pdf |
| Cover | : | cover.pdf |
| Daftar isi | : | daftar isi.pdf |
| Preliminary | : | preliminari.pdf |