Informasi Detail
| Call Number | : | 613 Put f 2014 - 1 |
| Judul | : | Formulasi Dan Evaluasi Oral Diintegrating Tablet Loperamide HCL Dengan Menggunakan Crosscarmellose Sodium Sebagai Superdisintegran |
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| Judul Seri | : | |
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| Pengarang | : | PUTRA \ 09613193 REZA ARGA PEMBIMBING: Syukri Yandi KUSUMA ARIS PERDANA |
| Subyek | : | 1.ORAL DISINTEGRATING TABLET 2.LOPERAMIDE HCL 3.SUPERDISINTEGRAN |
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| Abstrak | : | Loperamide HCl is Antidiarrhoeal medicine provided through oral with first-pass metabolism so the biological availability of oral only 0.3%. Oral disintegration loperamide HCL tablet will allow drug effectively. This research aims to know the influence of crosscarmellose sodium as superdisintegran to physical properties of Loperamide HCl. Tablets were formulated with a variety of levels of superdisintegran croscarmellose sodium with a concentration of 0.5%, 1.25%, 2.5%, 3.75%, and 5%. Tablet was prepared by direct compression method. Physical stability of the tablets were tested include disintegration time, etting time and disolution. The research showed that he increase concentration of crosscarmellose sodium will decrease wetting time and disintegration time while the disolution will increase. Formula with containing 5% croscarmellose sodium get the best loperamide HCl ODT. Key words: Oral Disintegrating Tablet, loperamide HCl, superdisintegran |
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| Lokasi | : | Perpustakaan Pusat UII |
| Jenis | : | Skripsi |
| DDC | : | 613 |
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| Penerbit | : | Jurusan Farmasi FMIPA UII |
| Tahun Terbit | : | 2014 |
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| ISBN / ISSN | : | / |
| Jumlah Eksemplar | : | 1 |
| Jumlah Tersedia | : | 0 |
| Jumlah Ditempat | : | 0 |
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| Informasi Digital | ||
| Abstrak | : | abstract.pdf |
| Cover | : | cover.pdf |
| Daftar isi | : | daftar isi.pdf |
| Preliminary | : | preliminari.pdf |